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Perioperative NSAIDs on Pain & Opioid Consumption After Spine Surgery: A Meta-Analysis

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Ace Report Cover
July 2024

Perioperative NSAIDs on Pain & Opioid Consumption After Spine Surgery: A Meta-Analysis

Vol: 306| Issue: 7| Number:40| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

The impact of perioperative nonsteroidal anti-inflammatory drugs on the postoperative outcomes of spinal surgery: a meta-analysis of 23 randomized controlled trials.

Neurosurg Rev . 2024 Apr 5;47(1):140.

Contributing Authors:
M Luo G Yang H Dai F Shi Z Tang J Tan Y Kang J Jiang J Xie Z Yi B Zhou Z Chen H Wang D Kong Z Xiao

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Synopsis

Twenty-three randomized controlled trials including 1457 patients undergoing spinal surgery were included in this systematic review and meta-analysis comparing the perioperative use of NSAIDs vs. no NSAIDs. Pooled outcomes of interest included postoperative morphine consumption and pain scores. The meta-analysis showed that NSAIDs significantly reduced postoperative morphine use and pain scores. T...

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