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The Safety & Efficacy of Perioperative Glucocorticoid for Total Knee Arthroplasty: A Meta-Analysis

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Ace Report Cover
June 2024

The Safety & Efficacy of Perioperative Glucocorticoid for Total Knee Arthroplasty: A Meta-Analysis

Vol: 306| Issue: 6| Number:45| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

The efficacy and safety of perioperative glucocorticoid for total knee arthroplasty: a systematic review and meta-analysis.

BMC Anesthesiol . 2024 Apr 15;24(1):144.

Contributing Authors:
F Liu M Duan H Fu T Wang

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Synopsis

Thirty-six randomized controlled trials including 3,048 patients who underwent primary unilateral total knee arthroplasty were included in this systematic review and meta-analysis comparing perioperative glucocorticoids vs. standard care. Pooled outcomes of interest included postoperative pain (VAS scores), morphine consumption, inflammatory cytokine levels (CRP and IL-6), range of motion, adverse...

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