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Topical Vancomycin For Preventing Fracture-Related Infections For Closed Fractures
June 2024
Topical Vancomycin For Preventing Fracture-Related Infections For Closed Fractures
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Does topical vancomycin prevent fracture-related infections in closed fractures undergoing open reduction and internal fixation? A randomised controlled trial.
Chin J Traumatol . 2024 Mar;27(2):71-76.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
96 patients with closed fractures undergoing open reduction and internal fixation were randomized to receive either topical vancomycin powder plus systemic antibiotic prophylaxis (n=48) or systemic antibiotic prophylaxis alone (n=48). The primary outcome of interest was the incidence of fracture-related infection (FRI). Secondary outcomes included clinical signs of infection, radiological evidence...
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