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Duloxetine For Pain & Opioid Consumption After Total Knee or Hip Arthroplasty: A Meta-Analysis
May 2024
Duloxetine For Pain & Opioid Consumption After Total Knee or Hip Arthroplasty: A Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effect of duloxetine on pain and opioid consumption after total knee and hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
Int J Clin Pharm . 2024 Feb;46(1):14-25.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
This systematic review and meta-analysis included nine randomized controlled trials involving 806 patients undergoing total knee and hip arthroplasty. The study compared perioperative administration of duloxetine to placebo, focusing on outcomes such as visual Analog Scale (VAS) pain scores at rest and during ambulation, postoperative opioid consumption quantified as oral morphine milligram equiva...
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