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Oral Midodrine for Post-Spinal Anesthesia Hypotension During Hip Arthoplasty

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Ace Report Cover
May 2024

Oral Midodrine for Post-Spinal Anesthesia Hypotension During Hip Arthoplasty

Vol: 306| Issue: 5| Number:66| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Oral midodrine for prophylaxis against post-spinal anesthesia hypotension during hip arthroplasty in elderly population: a randomized controlled trial.

BMC Anesthesiol . 2024 Feb 14;24(1):64.

Contributing Authors:
S Amin A Hasanin R Mansour M Mostafa D Zakaria AS Arafa A Yassin H Ziada

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Synopsis

58 elderly patients undergoing hip arthroplasty under spinal anesthesia were randomized to receive either 5 mg oral midodrine (n=29) or a placebo (n=29). The primary outcome of interest was intraoperative ephedrine consumption. Secondary outcomes included the incidence of post-spinal hypotension, bradycardia, hypertension, mean arterial pressure (MAP), and heart rate (HR). Outcomes were assessed t...

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