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Skin Antisepsis Before Surgical Fixation of Limb Fractures: The PREPARE Trial
January 2024
Skin Antisepsis Before Surgical Fixation of Limb Fractures: The PREPARE Trial
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Skin antisepsis before surgical fixation of limb fractures
NEJM. 2024 01-Jan;():.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
The PREPARE Trial was a cluster-randomized, crossover trial part of the PREP-IT program, which compared alcohol-based anti-septic solutions of iodine povacrylex vs. chlorhexidine gluconate in operative fracture patients. THE PREPARE Trial included a total of 8485 patients who underwent fracture fixation: 1700 patients with open limb fractures and 6785 with closed lower-limb or pelvic fractures. Ra...
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