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No Difference in Outcomes Between Coated and Uncoated Total Knee Arthroplasty
August 2025
No Difference in Outcomes Between Coated and Uncoated Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
No difference in patient reported outcome and inflammatory response after coated and uncoated total knee arthroplasty - a randomized controlled study.
BMC Musculoskelet Disord . 2023 Dec 14;24(1):968.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy‑six patients undergoing primary TKA were randomized to an uncoated cobalt‑chromium implant (n=38) or the same system with a seven‑layer Advanced Surface (zirconium‑nitride) coating (n=34). The primary outcome was systemic inflammatory response profiled by serum cytokines (IL‑1β, IL‑5, IL‑6, IL‑8, IL‑10, IFN‑γ, TNF‑α). Secondary outcomes included PROMs (Oxford Knee Score, Knee Society Score...
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