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Tranexamic Acid + Dexamethasone for Lower Limb Total Arthroplasty: A Meta-Analysis
August 2024
Tranexamic Acid + Dexamethasone for Lower Limb Total Arthroplasty: A Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effects of combined dexamethasone and tranexamic acid in lower limb total arthroplasty: a systematic review and meta-analysis of randomized clinical trials.
Eur J Orthop Surg Traumatol . 2023 Dec;33(8):3327-3335.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Three randomized controlled trials (288 patients) comparing tranexamic acid (TXA) + dexamethasone (DEX) against TXA alone in patients undergoing total hip or knee arthroplasty were included in this systematic review and meta-analysis. The primary outcome of interest was the incidence of oxycodone use. Secondary outcomes included total blood loss, the incidence of postoperative nausea and vomiting ...
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