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Tranexamic Acid Vs Epsilon-Aminocaproic Acid For Total Knee Arthroplasty: A Meta-Analysis

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Ace Report Cover
July 2024

Tranexamic Acid Vs Epsilon-Aminocaproic Acid For Total Knee Arthroplasty: A Meta-Analysis

Vol: 306| Issue: 7| Number:48| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Comparison of efficacy between tranexamic acid and epsilon-aminocaproic acid for total knee arthroplasty: A meta-analysis of randomized controlled trials.

Medicine (Baltimore) . 2023 Nov 24;102(47):e33876.

Contributing Authors:
J Li Y Guo M Li

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Synopsis

Six randomized controlled trials (739 patients) comparing tranexamic acid (TXA) against epsilon-aminocaproic acid (EACA) were included in this systematic review and meta-analysis. Outcomes of interest included the incidence of transfusion, decrease in hemoglobin, total blood loss, intraoperative blood loss, operative time, tourniquet time, and the incidence of deep vein thrombosis. All outcomes we...

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