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Oral Cannabidiol + Paracetamol For Chronic Knee Osteoarthritis
July 2024
Oral Cannabidiol + Paracetamol For Chronic Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trial.
Lancet Reg Health Eur . 2023 Nov 10:35:100777.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty-six patients with chronic symptomatic knee osteoarthritis were randomized to receive either high-dose cannabidiol (CBD; n=43) or placebo (n=43) as an add-on to continued paracetamol. The primary outcome of interest was the change in the Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) pain subscale over 8 weeks. Secondary outcomes included changes in WOMAC stiffness a...
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