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Tranexamic Acid Is Safe In Hemophilic Arthritis Patients Undergoing TKA Without Chemoprophylaxis
June 2025
Tranexamic Acid Is Safe In Hemophilic Arthritis Patients Undergoing TKA Without Chemoprophylaxis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study.
Knee. 2023 Oct:44:165-171.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred four patients with hemophilic arthritis underwent total knee arthroplasties and were randomized to receive either tranexamic acid (TXA) (n=52) or no TXA (n=52). All patients received modified coagulation factor substitution therapy and mechanical prophylaxis (no chemoprophylaxis). The primary outcome was the incidence of deep venous thrombosis (DVT), with secondary outcomes including b...
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