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The Safety & Efficacy of Duloxetine After TKA or THA: A Meta-Analysis
February 2024
The Safety & Efficacy of Duloxetine After TKA or THA: A Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The efficacy and safety of duloxetine for the treatment of patients after TKA or THA: A systematic review and meta-analysis.
Medicine (Baltimore) . 2023 Aug 25;102(34):e34895.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
8 randomized controlled trials (739 patients) comparing the use of duloxetine or placebo in patients undergoing either total knee or hip arthroplasty (TKA & THA, respectively) were included in this systematic review and meta-analysis. Outcomes of interest included opioid consumption, pain during rest and during walking on a Visual Analog Scale (VAS), pain on a Numeric Rating Scale (NRS), Knee Inju...
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