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Measuring the Ratio of MMP-1:TIMP-1 After Prolotherapy For Frozen Shoulder

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Ace Report Cover
March 2024

Measuring the Ratio of MMP-1:TIMP-1 After Prolotherapy For Frozen Shoulder

Vol: 306| Issue: 3| Number:10| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

The level of ratio between matrix metalloproteinase-1 (MMP-1) and tissue inhibitor matrix metalloproteinase-1 (TIMP-1) after prolotherapy intervention and the functional outcome in patient with frozen shoulder: A randomized controlled trial.

Medicine (Baltimore) . 2023 Jul 28;102(30):e34356.

Contributing Authors:
N Sam I Yusuf I Idris E Adnan RD Haryadi F Hamid A Usman MP Johan AA Zainuddin A Bukhari

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Synopsis

51 patients between the ages of 35 and 70 years with chronic frozen shoulder (FS) were included in this retrospective, double blind trial in which patients were randomly allotted to undergo prolotherapy (PT; n=19) or normal saline injections (NS; n=20). The primary outcomes of interest was the change in the ratio of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of matrix metalloproteinas...

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