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Aceclofenac & Ilaprazole vs Celecoxib for NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients
October 2023
Aceclofenac & Ilaprazole vs Celecoxib for NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of Aceclofenac and Ilaprazole Combination Therapy versus Celecoxib Monotherapy for Treating NSAID-Induced Dyspepsia in Lumbar Spinal Stenosis Patients.
Medicina (Kaunas). 2023 Jul; 59(7): 1307.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
128 patients with lumbar spinal stenosis who were receiving continuous non-selective nonsteroidal anti-inflammatory drugs (NSAIDs) were randomized to receive either a COX-2 selective NSAID (celecoxib; n=64) or a combination of an NSAID (aceclofenac) and a proton pump inhibitor (ilaprazole) (n=64). The primary outcome of interest was the severity of dyspepsia, as measured by the Short-Form Leeds Dy...
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