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Intramuscular Thiocolchicoside-Diclofenac vs. Diclofenac Monotherapy for Low Back Pain

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Ace Report Cover
August 2023

Intramuscular Thiocolchicoside-Diclofenac vs. Diclofenac Monotherapy for Low Back Pain

Vol: 303| Issue: 8| Number:9| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A randomized controlled trial evaluating the short-term efficacy of a single-administration intramuscular injection with the fixed combination of thiocolchicoside-diclofenac versus diclofenac monotherapy in patients with acute moderate-to-severe low back

BMC Musculoskelet Disord. 2023 Jun 10;24(1): 476.

Contributing Authors:
K Iliopoulos P Koufaki S Tsilikas K Avramidis A Tsagkalis C Mavragani E Zintzaras

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Synopsis

One hundred and thirty-four patients with moderate-severe, acute low back pain were randomized to receive a single intramuscular injection of diclofenac-thiocolchicoside (n=68) or diclofenac only (n=66). The primary outcome of interest was the mean change in Visual Analog Scale (VAS) pain score from baseline to 3 hours. Secondary outcomes of interest include the percentage of patients showing a >3...

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