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Effect of Specialized Pro-Resolving Mediators on Pain for Knee Osteoarthritis: A Randomized Trial
July 2023
Effect of Specialized Pro-Resolving Mediators on Pain for Knee Osteoarthritis: A Randomized Trial
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Randomized, double-blind, placebo-controlled study to evaluate the effect of treatment with an SPMs-enriched oil on chronic pain and inflammation, functionality, and quality of life in patients with symptomatic knee osteoarthritis: GAUDI study.
J Transl Med. 2023 Jun 29;21(1): 423.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
51 patients with symptomatic knee osteoarthritis were randomized to receive 12 weeks of specialized pro-resolving mediators (SPM) supplementation via soft gels (n=23) or a placebo with olive oil (n=28). The primary outcome of interest was the change in Visual Analog Scale (VAS) pain score from baseline at 12 weeks follow-up. Secondary outcomes included joint function according to the Western Ontar...
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