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Combination of Mesenchymal Stem Cells & Platelet-Rich Plasma for Knee Osteoarthritis
January 2023
Combination of Mesenchymal Stem Cells & Platelet-Rich Plasma for Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Combination of mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) in the treatment of knee osteoarthritis: a meta-analysis of randomised controlled trials
BMJ Open. 2022 Nov 16;12(11):e061008Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Six controlled clinical trials containing a total of 493 patients with knee osteoarthritis were included in this systematic review and meta-analysis comparing the combination of mesenchymal stem cells and platelet-rich plasma (n=204) with control (n=289; mesenchymal stem cells, platelet-rich plasma, or hyaluronic acid alone). Pooled outcomes of interest included pain on a Visual Analog Scale (VAS)...
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