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Parecoxib for Postoperative Pain and Opioid Consumption after Orthopaedic Surgery
November 2022
Parecoxib for Postoperative Pain and Opioid Consumption after Orthopaedic Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Intravenous Parecoxib for Pain Relief after Orthopedic Surgery: A Systematic Review and Meta-analysis
Pain Ther . 2022 Sep;11(3):771-787.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
A meta-analysis of twenty-seven randomized controlled trials was conducted to compare the effect of intravenous parecoxib on postoperative pain and opioid consumption compared to a placebo or other active treatment. Subgroup analyses of surgery types (lumbar spine, hip/knee arthroplasty, other surgery) were also conducted. Pain scores at rest favoured the parecoxib group at 12h, 24h, and 48h after...
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