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Vol:294 Issue:1 Number:6 ISSN#:2564-2537
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RCT
ACE Report #14991
Ace Report Cover Osteoarthritis

Platelet-Rich Plasma vs. Novel Cross-linked Hyaluronic Acid Injection for Early Knee Osteoarthritis


How to Cite

OrthoEvidence. Platelet-Rich Plasma vs. Novel Cross-linked Hyaluronic Acid Injection for Early Knee Osteoarthritis. ACE Report. 2022;294(1):6. Available from: https://myorthoevidence.com/AceReport/Report/14991

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Comparing the Efficacy of Intra-Articular Single Platelet-Rich Plasma(PRP) versus Novel Crosslinked Hyaluronic Acid for Early-Stage Knee Osteoarthritis: A Prospective, Double-Blind, Randomized Controlled Trial

Medicina (Kaunas). 2022 Aug 1;58(8): 1028.

Contributing Authors:
YC Wang CL Lee YJ Chen YC Tien SY Lin CH Chen PP Chou HT Huang

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Synopsis

116 patients with early-stage knee osteoarthritis were randomized to receive a single intra-articular injection of a novel cross-linked hyaluronic acid (HA; n=58) or platelet-rich plasma (PRP; n=58). The outcome of interest was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and associated sub-scores, measured at 1, 3 and 6 months follow-up. Results revealed similar scor...

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