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Comparative Benefits and Harms of Individual Opioids for Chronic Non-cancer Pain
July 2022
Comparative Benefits and Harms of Individual Opioids for Chronic Non-cancer Pain
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparative benefits and harms of individual opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised trials
Br J Anaesth. 2022 Jul 8;S0007-0912(22)00288-4.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
82 randomized controlled trials including 22,619 patients with chronic non-cancer pain were included in this network meta-analysis investigating the relative benefits and harms of individual opioids in both extended-release (ER) and immediate-release (IR) formulations. Outcomes of interest included pain relief, function, and gastrointestinal adverse events (vomiting; constipation; nausea). Results...
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