Comparative Benefits and Harms of Individual Opioids for Chronic Non-cancer Pain
How to Cite
OrthoEvidence. Comparative Benefits and Harms of Individual Opioids for Chronic Non-cancer Pain. ACE Report. 2022;270(1):1. Available from: https://myorthoevidence.com/AceReport/Report/14815
Comparative benefits and harms of individual opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised trialsBr J Anaesth. 2022 Jul 8;S0007-0912(22)00288-4.
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82 randomized controlled trials including 22,619 patients with chronic non-cancer pain were included in this network meta-analysis investigating the relative benefits and harms of individual opioids in both extended-release (ER) and immediate-release (IR) formulations. Outcomes of interest included pain relief, function, and gastrointestinal adverse events (vomiting; constipation; nausea). Results...
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