Intraoperative Ketamine vs Placebo for Rebound Pain in Upper Limb Surgeries
Evaluation of intraoperative ketamine on the prevention of severe rebound pain upon cessation of peripheral nerve block: a prospective randomised, double-blind, placebo-controlled study.Br J Anaesth . 2022 Apr;128(4):734-741.
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One hundred and nine patients undergoing upper limb surgery under an axillary plexus block were randomized to receive either intraoperative ketamine (n = 54) or placebo (n = 55; saline) for the prevention of severe rebound pain upon the cessation of a peripheral nerve block. All patients received an optimal preoperative multimodal analgesic treatment including intraoperative ketorolac and paraceta...
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