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Vol:255 Issue:3 Number:28 ISSN#:2564-2537
ACE Report #14648
Ace Report Cover Trauma

Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fracture Surgery

How to Cite

OrthoEvidence. Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fracture Surgery. ACE Report. 2022;255(3):28. Available from:

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Tranexamic acid safely reduces hidden blood loss in patients undergoing intertrochanteric fracture surgery: a randomized controlled trial.

Eur J Trauma Emerg Surg. 2022 Apr;48(2): 731-741.

Contributing Authors:
S Zhang C Xiao W Yu N Long F He P Cai K Luo Y Jiang

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122 patients undergoing intertrochanteric fracture surgery were randomized to receive two doses of 1g tranexamic acid delivered intravenously prior and after surgery (n=61) or placebo (n=61). The primary outcome of interest was hidden blood loss. Secondary outcomes of interest included intraoperative and total blood loss, hemoglobin levels and drop, transfusion rate, and the incidence of complicat...

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