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Strong vs. Weak Opioids For Outpatient Analgesia After Surgically Managed Fractures
January 2022
Strong vs. Weak Opioids For Outpatient Analgesia After Surgically Managed Fractures
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effectiveness of Oxycodone Hydrochloride (Strong Opioid) vs Combination Acetaminophen and Codeine (Mild Opioid) for Subacute Pain After Fractures Managed Surgically: A Randomized Clinical Trial.
JAMA Netw Open . 2021 Nov 1;4(11):e2134988.Synopsis
One hundred and twenty patients undergoing surgical fixation of fractures were randomized to receive a strong opioid (Oxycodone, n=59) or a weak opioid (Acetaminophen and codeine, n=61) at the time of discharge from hospital. The primary outcome of interest was mean pain scores for the first week after discharge from hospital as measured by the Numerical Pain Rating Scale (NPRS). Secondary outcome...
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