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Vol:141 Issue:1 Number:1 ISSN#:2564-2537
Author Verified
ACE Report #14122
Ace Report Cover Osteoarthritis

Dietary Hyaluronan, Glucosamine, and Chondroitin Mix for Moderate Pain from Knee Osteoarthritis

How to Cite

OrthoEvidence. Dietary Hyaluronan, Glucosamine, and Chondroitin Mix for Moderate Pain from Knee Osteoarthritis. ACE Report. 2021;141(1):1. Available from:

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Liquid combination of hyaluronan, glucosamine, and chondroitin as a dietary supplement for knee osteoarthritis patients with moderate knee pain: A randomized controlled study

Medicine (Baltimore). 2021 Oct 8;100(40): e27405.

Contributing Authors:
SJ Wang YH Wang LC Huang

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Ninety-seven patients reporting moderate pain from knee osteoarthritis were randomized to receive 8 weeks of daily dietary supplementation with a oral mixture of hyaluronic acid, glucosamine, and chondroitin (n=47) or an oral placebo (n=50). The primary outcome of interest was the change from baseline in Knee Injury and Osteoarthritis Outcomes Scores (KOOS). Secondary outcomes of interest included...

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