Diclofenac-Hyaluronate Conjugate Injection for Knee Osteoarthritis
How to Cite
OrthoEvidence. Diclofenac-Hyaluronate Conjugate Injection for Knee Osteoarthritis . ACE Report. 2021;111(1):2. Available from: https://myorthoevidence.com/AceReport/Report/13976
Efficacy and Safety of Diclofenac-Hyaluronate Conjugate (Diclofenac Etalhyaluronate) for Knee Osteoarthritis: A Randomized Phase III Trial in Japan.Arthritis Rheumatol. 2021 Sep;73(9): 1646-1655.
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Four hundred and forty patients with knee osteoarthritis were randomized to receive a series of intra-articular diclofenac-hyaluronate conjugate (Diclofenac Etalhyaluronate) injections (DF-HA) (n=220) or placebo injections (n=220). The primary outcome of interest was the change in baseline in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale. Secondary outcom...
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