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Volume:99 Issue:1 Number:1 ISSN#:2564-2537
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ACE Report #13928
Ace Report Cover Trauma

Topical Tranexamic Acid Reduces Blood Loss in Hip Fractures


How to Cite

OrthoEvidence. Topical Tranexamic Acid Reduces Blood Loss in Hip Fractures. ACE Report. 2021;99(1):1. Available from: https://myorthoevidence.com/AceReport/Report/13928

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study.

Can J Surg. 2021 Aug 10;64(4): E449-E456.

Contributing Authors: D Costain G Elder B Fraser B Slagel A Kelly Y Cheong L Fera

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Synopsis

Seventy four patients undergoing operative management for a hip fracture were randomized to receive intraoperative topical tranexamic acid (TXA) (n=31) or a placebo (n=34). Outcomes of interest were postoperative hemoglobin levels, transfusion rates and adverse events. The TXA group demonstrated significantly higher hemoglobin levels on postoperative days 1 and 2. When excluding intraoperative tra...

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