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Tranexamic Acid Reduces Blood Loss After Anatomic and Reverse Total Shoulder Arthroplasty

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Ace Report Cover
August 2021

Tranexamic Acid Reduces Blood Loss After Anatomic and Reverse Total Shoulder Arthroplasty

Vol: 76| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A single dose of tranexamic acid reduces blood loss after reverse and anatomic shoulder arthroplasty: a randomized controlled trial.

J Shoulder Elbow Surg. 2021 Jul;30(7): 1553-1560.

Contributing Authors:
G Cunningham J Hughes B Borner O Mattern ME Taha MM Smith AA Young B Cass

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Synopsis

Sixty patients were randomized to receive a single dose of 2g of intravenous tranexamic acid (TXA) (n=31) or placebo (n=29) prior to undergoing an anatomic or reverse total shoulder arthroplasty. Outcomes of interest included postoperative hemoglobin and hematocrit levels, drain outputs, pain scores and length of stay. The TXA group had significantly higher postoperative hemoglobin, lower changes ...

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