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Safety and Efficacy of an Amniotic Suspension Allograft Injection for Symptomatic Knee OA

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Ace Report Cover
August 2021

Safety and Efficacy of an Amniotic Suspension Allograft Injection for Symptomatic Knee OA

Vol: 79| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Safety and Efficacy of an Amniotic Suspension Allograft Injection Over 12 Months in a Single-Blinded, Randomized Controlled Trial for Symptomatic Osteoarthritis of the Knee.

Arthroscopy. 2021 Jul;37(7): 2246-2257.

Contributing Authors:
AH Gomoll J Farr BJ Cole DC Flanigan C Lattermann BR Mandelbaum SM Strickland KR Zaslav KA Kimmerling KC Mowry

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Synopsis

Two-hundred patients with moderate, symptomatic knee osteoarthritis were randomized to receive an intra-articular injection of amniotic suspension allograft (ASA; n=68), hyaluronic acid (HA; n=64) or normal saline (n=68). Outcomes of interest included the change from baseline at 12 months in the Knee Injury and Osteoarthritis Outcome Score (KOOS) subsets (pain; symptoms; activities of daily living...

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