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Efficacy of Bisphosphonate Analogs for Treatment of Osteoporosis After Spinal Cord Injury
August 2021
Efficacy of Bisphosphonate Analogs for Treatment of Osteoporosis After Spinal Cord Injury
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The efficacy and safety of bisphosphonate analogs for treatment of osteoporosis after spinal cord injury: a systematic review and meta-analysis of randomized controlled trials
Osteoporos Int. 2021 Jun;32(6): 1117-1127.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Nine randomized controlled trials containing 406 patients with osteoporosis after spinal cord injury were included in this meta-analysis comparing bisphosphonate analogs (n=104) to control (n=102) for the prevention of bone density loss. The primary outcome of interest was the change in bone mineral density (BMD) of the total hip, distal femur, and lumbar spinal regions. Results revealed a signifi...
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