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Efficacy of Combined Conservative Therapies vs Education in Thumb Base Osteoarthritis
March 2025
Efficacy of Combined Conservative Therapies vs Education in Thumb Base Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of a Combination of Conservative Therapies vs an Education Comparator on Clinical Outcomes in Thumb Base Osteoarthritis: A Randomized Clinical Trial
JAMA Intern Med. 2021 Apr 1;181(4):429-438.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Two hundred four patients with symptomatic and radiographic thumb base osteoarthritis were randomized to receive a 6-week combination of education, splinting, hand exercises, and topical diclofenac sodium 1% gel (n=102) or education alone (n=102). The primary outcomes were hand function (Functional Index for Hand Osteoarthritis, FIHOA) and thumb base pain (visual analog scale, VAS). Secondary outc...
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