Effect of Supplemental Vitamin C on Function in Patients Suffering from Orthopaedic Disorders

How to Cite

OrthoEvidence. Effect of Supplemental Vitamin C on Function in Patients Suffering from Orthopaedic Disorders. ACE Report. 2021;34(1):5. Available from: https://myorthoevidence.com/AceReport/Report/13558

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

A meta-analysis of randomized clinical trials on the impact of oral vitamin C supplementation on first-year outcomes in orthopedic patients

Sci Rep. 2021 Apr 29;11(1): 9225.

Contributing Authors: KC Hung MH Chiang SC Wu YJ Chang CN Ho LK Wang JY Chen KH Chen CK Sun

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Synopsis

Seven randomized controlled trials with a total of 1361 patients suffering from orthopaedic disorders requiring surgical or conservative management therapy were included in this meta-analysis comparing supplemental oral/intravenous Vitamin C (n=797) or no therapy (n=564). The primary outcome of interest was function, which was evaluated at 3-6 and 6-12 months follow-up. Secondary outcomes included...