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PRP Improves Pain, Stiffness & Function vs HA Injection in Knee Osteoarthritis Patients Up to 1 Year

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Ace Report Cover
April 2021

PRP Improves Pain, Stiffness & Function vs HA Injection in Knee Osteoarthritis Patients Up to 1 Year

Vol: 23| Issue: 1| Number:3| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Clinical therapy of platelet-rich plasma vs hyaluronic acid injections in patients with knee osteoarthritis: A systematic review and meta-analysis of randomized double-blind controlled trials

Medicine (Baltimore). 2021 Mar 26;100(12): e25168.

Contributing Authors:
H Gong K Li R Xie G Du L Li S Wang J Yin J Gu P Wang M Chen X Hou

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Synopsis

Six randomized controlled trials with a total of 661 patients with knee osteoarthritis (OA) were randomized to receive platelet-rich plasma injection therapy (PRP; n=338) or hyaluronic acid (HA; n=323). Primary outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Total Score and WOMAC physical function score. Secondary outcomes of interest includ...

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