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Effect of Neuromuscular Blockade Depth on Inflammation and Clinical Outcomes in Elderly THA Patients
April 2021
Effect of Neuromuscular Blockade Depth on Inflammation and Clinical Outcomes in Elderly THA Patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effect of deep neuromuscular blockade on serum cytokines and postoperative delirium in elderly patients undergoing total hip replacement: A prospective single-blind randomised controlled trial
Eur J Anaesthesiol. 2021 Mar 1;38(Suppl 1): S58-S66Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty-two elderly patients with hip fracture scheduled for a total hip replacement under general anesthesia were randomized to receive a deep neuromuscular blockade (n=41) or a moderate neuromuscular blockade (n=41) for the facilitation of tissue manipulation during surgery. Outcomes of interest included inflammatory markers (interleukin [IL]-1b; IL-6; tumour necrosis factor [TNF] alpha; IL-10), ...
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