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Volume:21 Issue:1 Number:4 ISSN#:2563-5476
RCT
ACE Report #13448
Ace Report Cover Arthroplasty

Effect of Neuromuscular Blockade Depth on Inflammation and Clinical Outcomes in Elderly THA Patients


How to Cite

OrthoEvidence. Effect of Neuromuscular Blockade Depth on Inflammation and Clinical Outcomes in Elderly THA Patients. ACE Report. 2021;21(1):4. Available from: https://myorthoevidene.com/AceReport/Report/13448

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of deep neuromuscular blockade on serum cytokines and postoperative delirium in elderly patients undergoing total hip replacement: A prospective single-blind randomised controlled trial

Eur J Anaesthesiol. 2021 Mar 1;38(Suppl 1): S58-S66

Contributing Authors: CS Oh HY Lim HJ Jeon TH Kim HJ Park L Piao SH Kim

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Synopsis

Eighty-two elderly patients with hip fracture scheduled for a total hip replacement under general anesthesia were randomized to receive a deep neuromuscular blockade (n=41) or a moderate neuromuscular blockade (n=41) for the facilitation of tissue manipulation during surgery. Outcomes of interest included inflammatory markers (interleukin [IL]-1b; IL-6; tumour necrosis factor [TNF] alpha; IL-10), ...

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