Bone Turnover Marker Monitoring for Guiding Osteoporosis Treatment Post-TKA In Post-Menopausal Women

How to Cite

OrthoEvidence. Bone Turnover Marker Monitoring for Guiding Osteoporosis Treatment Post-TKA In Post-Menopausal Women. ACE Report. 2021;21(1):2. Available from: https://myorthoevidene.com/AceReport/Report/13439

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

The use of bone turnover markers for monitoring the treatment of osteoporosis in postmenopausal females undergoing total knee arthroplasty: a prospective randomized study

J Orthop Surg Res. 2021 Mar 17;16(1): 195.

Contributing Authors: R Ma M Wu Y Li J Wang P Yang Y Chen W Wang J Song K Wang

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Synopsis

Sixty-four post-menopausal women with osteoporosis scheduled for a unilateral total knee arthroplasty (TKA) were randomized to receive anti-osteoporosis treatment (alendronate; calcitriol; calcium carbonate) guided by bone turnover marker monitoring (n=32) or a standard 3 month anti-osteoporosis treatment (n=32). Outcomes of interest included duration of treatment, incidence of adverse reactions t...