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Volume:14 Issue:1 Number:2 ISSN#:2563-5476
RCT
ACE Report #13276
Ace Report Cover General Orthopaedics

Reduction in PGE2 Levels with Photobiomodulation Therapy vs Sham for Non-Specific Low Back Pain


How to Cite

OrthoEvidence. Reduction in PGE2 Levels with Photobiomodulation Therapy vs Sham for Non-Specific Low Back Pain. ACE Report. 2021;14(1):2. Available from: https://myorthoevidene.com/AceReport/Report/13276

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Photobiomodulation Therapy is Able to Modulate PGE 2 Levels in Patients With Chronic Non-Specific Low Back Pain: A Randomized Placebo-Controlled Trial

Lasers Surg Med. 2021 Feb;53(2): 236-244.

Contributing Authors: SS Tomazoni LOP Costa J Joensen MB Stausholm IF Naterstad M Ernberg ECP Leal-Junior JM Bjordal

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Synopsis

Eighteen patients with chronic non-specific low back pain were randomized to receive a single session of photobiomodulation therapy (n=9) or sham therapy (n=9) for the modulation of inflammatory markers and relief of pain. The primary outcome of interest was prostaglandin E2 (PGE2) levels. Secondary outcomes of interest included tumour necrosis factor alpha (TNF-a), interleukin (IL)-6 levels, and ...

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