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Reduction in PGE2 Levels with Photobiomodulation Therapy vs Sham for Non-Specific Low Back Pain
March 2021
Reduction in PGE2 Levels with Photobiomodulation Therapy vs Sham for Non-Specific Low Back Pain
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Photobiomodulation Therapy is Able to Modulate PGE 2 Levels in Patients With Chronic Non-Specific Low Back Pain: A Randomized Placebo-Controlled Trial
Lasers Surg Med. 2021 Feb;53(2): 236-244.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighteen patients with chronic non-specific low back pain were randomized to receive a single session of photobiomodulation therapy (n=9) or sham therapy (n=9) for the modulation of inflammatory markers and relief of pain. The primary outcome of interest was prostaglandin E2 (PGE2) levels. Secondary outcomes of interest included tumour necrosis factor alpha (TNF-a), interleukin (IL)-6 levels, and ...
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