Dexmedetomidine as Adjunct to Local Anesthetic Improves Pain, Function & Satisfaction After TKA

How to Cite

OrthoEvidence. Dexmedetomidine as Adjunct to Local Anesthetic Improves Pain, Function & Satisfaction After TKA. ACE Report. 2021;10(1):16. Available from: https://myorthoevidene.com/AceReport/Report/12883

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Dexmedetomidine as an adjunct to local anesthetics in nerve block relieved pain more effectively after TKA: a meta-analysis of randomized controlled trials.

J Orthop Surg Res. 2020 Dec 1;15(1):577.

Contributing Authors: L Pan H Wu H Liu X Yang Z Meng Y Cao

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Synopsis

Seven studies including a total of 546 patients undergoing primary total knee arthroplasty (TKA) were included in this meta-analysis comparing dexmedetomidine as an adjunct to local anesthesia in nerve blockade or local anesthesia alone. The primary outcomes of interest included the pooled pain scores at rest and during motion. Secondary outcomes of interests included pooled opioid consumption, an...