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Peri-Operative Mepivacaine in THA Achieves Earlier Ambulation & Shorter Hospital Stay vs Bupivacaine

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January 2021

Peri-Operative Mepivacaine in THA Achieves Earlier Ambulation & Shorter Hospital Stay vs Bupivacaine

Vol: 10| Issue: 1| Number:7| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation

Anesthesiology. 2020 Oct 1;133(4):801-811.

Contributing Authors:
Schwenk ES Kasper VP Smoker JD Mendelson AM Austin MS Brown SA Hozack WJ Cohen AJ Li JJ Wahal CS Baratta JL Torjman MC Nemeth AC Czerwinski EE

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Synopsis

One hundred and fifty-nine patients scheduled for a primary total hip arthroplasty were randomized to receive spinal anesthesia with hyperbaric bupivacaine (n=54), isobaric bupivacaine (n=52), or mepivacaine (n=53). Primary outcome of interest was the percentage of patients achieving ambulation within 3-3.5 hours. Secondary outcomes of interest included the time to motor function return, initial d...

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