Peri-Operative Mepivacaine in THA Achieves Earlier Ambulation & Shorter Hospital Stay vs Bupivacaine

How to Cite

OrthoEvidence. Peri-Operative Mepivacaine in THA Achieves Earlier Ambulation & Shorter Hospital Stay vs Bupivacaine. ACE Report. 2021;10(1):7. Available from: https://myorthoevidene.com/AceReport/Report/12858

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation

Anesthesiology. 2020 Oct 1;133(4):801-811.

Contributing Authors: Schwenk ES Kasper VP Smoker JD Mendelson AM Austin MS Brown SA Hozack WJ Cohen AJ Li JJ Wahal CS Baratta JL Torjman MC Nemeth AC Czerwinski EE

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Synopsis

One hundred and fifty-nine patients scheduled for a primary total hip arthroplasty were randomized to receive spinal anesthesia with hyperbaric bupivacaine (n=54), isobaric bupivacaine (n=52), or mepivacaine (n=53). Primary outcome of interest was the percentage of patients achieving ambulation within 3-3.5 hours. Secondary outcomes of interest included the time to motor function return, initial d...