Acute Post-op Clinical Benefit with Transdermal Buprenorphine Patch vs Oral Celecoxib in TKA Patient

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Transdermal buprenorphine patch versus oral celecoxib for pain management after total knee arthroplasty: An open- label, randomized controlled trial.

Orthop Traumatol Surg Res. 2020 Sep;106(5):915-919.

Contributing Authors: X Xu L Xie H Liu Y Hu

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Synopsis

One hundred and sixty patients with knee osteoarthritis (OA) scheduled for a total knee arthroplasty were randomized to receive a transdermal buprenorphine patch or oral celecoxib for the relief of pain post-operation. Outcomes of interest included pain at rest and during activity on a Visual Analog Scale (VAS), range of motion, Lysholm Knee Scores, and the incidence of adverse events. Outcomes we...