PRP is Superior to HA for Symptomatic Knee Pain at 6 and 12 Months for Knee Osteoarthritis

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Is platelet-rich plasma effective for the treatment of knee osteoarthritis? A systematic review and meta-analysis of level 1 and 2 randomized controlled trials.

Eur J Orthop Surg Traumatol. 2020 Aug;30(6):955-967.

Contributing Authors: E Hohmann K Tetsworth V Glatt

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Synopsis

Twelve studies including 1,248 patients were included in this meta-analysis comparing intra-articular injections of platelet rich plasma (PRP) and intra-articular injection of hyaluronic acid (HA) for the treatment of knee osteoarthritis (OA). Pooled outcomes of interest included clinical outcome, assessed by Western Ontario and McMaster Universities (WOMAC) osteoarthritis index, Knee Injury and O...