Addition of Rifampin to Antimicrobial Therapy Does Not Improve Success Rate in Staphylococcal PJI
Rifampin combination therapy in staphylococcal prosthetic joint infections: a randomized controlled trial.J Orthop Surg Res. 2020; 15: 365.
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Sixty-five patients with staphylococcal peri-prosthetic joint infections of the hip or knee were randomized to receive debridement and wound excision plus 6 weeks of antimicrobial therapy (intravenous cloxacillin or vancomycin), with or without the addition of oral rifampin. The outcome of interest was treatment success at 2 years follow up, defined as a lack of clinical signs of peri-prosthetic j...
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