Addition of Rifampin to Antimicrobial Therapy Does Not Improve Success Rate in Staphylococcal PJI
How to Cite
OrthoEvidence. Addition of Rifampin to Antimicrobial Therapy Does Not Improve Success Rate in Staphylococcal PJI. ACE Report. 2020;9(9):19. Available from: https://myorthoevidene.com/AceReport/Report/12327
Rifampin combination therapy in staphylococcal prosthetic joint infections: a randomized controlled trial.J Orthop Surg Res. 2020; 15: 365.
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Sixty-five patients with staphylococcal peri-prosthetic joint infections of the hip or knee were randomized to receive debridement and wound excision plus 6 weeks of antimicrobial therapy (intravenous cloxacillin or vancomycin), with or without the addition of oral rifampin. The outcome of interest was treatment success at 2 years follow up, defined as a lack of clinical signs of peri-prosthetic j...
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