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Volume:8 Issue:9 Number:8 ISSN#:2563-5476
RCT
ACE Report #12320
Ace Report Cover General Orthopaedics

Low-Molecular Weight Heparin and Aspirin Provide Similar VTE Prevention in Trauma Fracture Patients


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Aspirin versus low-molecular-weight heparin for venous thromboembolism prophylaxis in orthopaedic trauma patients: A patient-centered randomized controlled trial.

PloS one. 2020 Aug 3;15(8):e0235628

Contributing Authors: BE Haac NN O'Hara TT Manson GP Slobogean RC Castillo RV O'Toole DM Stein Investigators ADAPT

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Synopsis

Three hundred and twenty-nine patients with a traumatic extremity fracture requiring operative treatment where venous thromboembolism prophylaxis was needed were randomized to receive either low-molecular weight heparin (LMWH) or aspirin. The primary outcome of interest included the incidence of mortality, bleeding, venous thromboembolism (VTE), deep surgical site infection, and a combination of t...

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