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Meta-analysis
ACE Report #12253
Ace Report Cover General Orthopaedics

Chlorhexidine vs Povidone-Iodine Skin Disinfectant for the Prevention of Surgical Site Infection


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Preoperative Antisepsis with Chlorhexidine Versus Povidone-Iodine for the Prevention of Surgical Site Infection: a Systematic Review and Meta-analysis

World J Surg. 2020 May;44(5):1412-1424. doi: 10.1007/s00268-020-05384-7.

Contributing Authors: S Chen JW Chen B Guo CC Xu

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Synopsis

Thirty studies containing 29,006 patients were included in this meta-analysis comparing chlorhexidine and povidone-iodine skin disinfectant solutions for the prevention of surgical site infection. The primary outcome of interest was the pooled incidence of post-operative surgical site infection. The secondary outcome of interest was the pooled incidence of skin-related adverse events. Sub-group an...

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