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No difference in deep infection rate with iNPWT and standard wound dressing in low fracture surgery

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Ace Report Cover
April 2020

No difference in deep infection rate with iNPWT and standard wound dressing in low fracture surgery

Vol: 9| Issue: 4| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on Deep Surgical Site Infection After Surgery for Lower Limb Fractures Associated With Major Trauma: The WHIST Randomized Clinical Trial.

JAMA. 2020 Feb 11;323(6):519-526.

Contributing Authors:
MatthewL Costa ML Costa Juul Achten J Achten J Bruce Ruth Knight Julie Bruce SJ Dutton M Dritsaki SusanJ Dutton Jason Madan N Parsons Melina Dritsaki M Fernandez Collaborators WHIST Trial Nick Parsons Miguel Fernandez R Knight R Grant Richard Grant Jagdeep Nanchahal J Nanchahal J Madan CollectiveName WHIST Trial Collaborators

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Synopsis

One thousand five hundred and forty-eight patients presenting with a lower extremity fracture caused by major trauma received surgical intervention followed by surgical wound dressing with an incisional negative pressure wound therapy (iNPWT) device or with standard sterile dressing. The primary outcome of interest was the incidence of deep surgical site infection within the first 30 days post-ope...

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