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Meta-analysis
ACE Report #12071
Ace Report Cover Arthroplasty

Similar pain, lower opioid consumption with addition of morphine to local multimodal cocktail in TKA


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of morphine added to multimodal cocktail on infiltration analgesia in total knee arthroplasty: A meta-analysis of randomized controlled trials

Medicine (Baltimore). 2019 Oct;98(41):e17503.

Contributing Authors: Y Zhang F Mi H Zhao D Xie X Shi

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Synopsis

8 randomized controlled trials were included in this meta-analysis comparing multimodal cocktail injections for use in local infiltration analgesia containing morphine vs. cocktails injections not containing morphine in patients undergoing total knee arthroplasties. Outcomes of interest included pain scores at rest and during motion, post-operative opioid consumption, range of motion, Western Onta...

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