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ACE Report #12059
Ace Report Cover Trauma

OTA 2019: Open fractures treated with vac dressing at higher risk of infection and lower HRQoL

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Does Negative Pressure Wound Therapy Reduce the Odds of Infection and Lower Health-Related Quality of Life in Open Fracture Patients?

Contributing Authors: Yousif Atwan EH Schemitch S Sprague Sofia Bozovsky K Jeray B Petrisor M Bhandari

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


Open fractures are common and potentially devastating. Their treatment remains focused on early irrigation and debridement. The question of whether negative pressure wound therapy is helpful remains unclear. The authors performed a secondary analysis of patients from the FLOW Trial who had Gustilo II and III lower extremity fractures. A propensity score matching system was applied to assess the ri...

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