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Low-dose ketamine reduces pain and opioid consumption following orthopaedic surgery
November 2019
Low-dose ketamine reduces pain and opioid consumption following orthopaedic surgery
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A
Low-dose ketamine in painful orthopaedic surgery: a systematic review and meta-analysis
Br J Anaesth. 2019 Sep;123(3):325-334.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Twenty studies with 1271 patients were included in this systematic review and meta-analysis comparing low-dose ketamine to normal saline in patients undergoing surgical orthopaedic procedures. The primary outcomes of interest were total opioid consumption, time to first opioid administration and pain scores. Secondary outcomes of interest included the incidences of post-operative nausea and vomiti...
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