Low-dose ketamine reduces pain and opioid consumption following orthopaedic surgery
Low-dose ketamine in painful orthopaedic surgery: a systematic review and meta-analysisBr J Anaesth. 2019 Sep;123(3):325-334.
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Twenty studies with 1271 patients were included in this systematic review and meta-analysis comparing low-dose ketamine to normal saline in patients undergoing surgical orthopaedic procedures. The primary outcomes of interest were total opioid consumption, time to first opioid administration and pain scores. Secondary outcomes of interest included the incidences of post-operative nausea and vomiti...
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