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OTA 2019: Improved bone healing with PLEX-DBG over control in open fracture surgery
November 2019
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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Non-union is a major concern in patients with long bone open fractures. Different strategies are available to reduce this risk, but high quality evidence remains elusive. The authors randomized 51 patients to receive PLEX-DBG (an antibiotic bone graft) or standard of care. Most patients had Gustilo III fractures. There was a significantly higher rate of callus formation in the PLEX-DBG group compa...
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