OTA 2019: Improved bone healing with PLEX-DBG over control in open fracture surgery

How to Cite

OrthoEvidence. OTA 2019: Improved bone healing with PLEX-DBG over control in open fracture surgery. ACE Report. 2019;8(11):8. Available from: https://myorthoevidene.com/AceReport/Report/12038

Study Type:N/A

OE Level Evidence:N/A

Journal Level of Evidence:N/A

Improved Healing of Severe Open Long Bone Fractures Treated with AntibioticFormulated Bone Graft During the First Surgical Intervention Post-Injury

Contributing Authors: D Norman M Salai Noam Emanuel

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

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Synopsis

Non-union is a major concern in patients with long bone open fractures. Different strategies are available to reduce this risk, but high quality evidence remains elusive. The authors randomized 51 patients to receive PLEX-DBG (an antibiotic bone graft) or standard of care. Most patients had Gustilo III fractures. There was a significantly higher rate of callus formation in the PLEX-DBG group compa...