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Volume:7 Issue:9 Number:21 ISSN#:2563-5476
RCT
ACE Report #12002
Ace Report Cover Sports Medicine

No difference in function between stem cells and control during microfracture


Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:2

Transplantation of autologous bone marrow-derived mesenchymal stem cells under arthroscopic surgery with microfracture versus microfracture alone for articular cartilage lesions in the knee: A multicenter prospective randomized control clinical trial

Regen Ther. 2019;(11):106-113. doi: 10.1016/j.reth.2019.06.002

Contributing Authors: Y Hashimoto Y Nishida S Takahashi H Nakamura H Mera K Kashiwa S Yoshiya Y Inagaki K Uematsu Y Tanaka S Asada M Akagi K Fukuda Y Hosokawa A Myoui N Kamei M Ishikawa N Adachi M Ochi S Wakitani

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Synopsis

The authors randomized 14 patients who were undergoing microfracture to two groups: one group received bone marrow-derived mesenchymal stem cells (BMSCs), and the other group were controls. Outcomes included the Knee Injury and Osteoarthritis Outcome Score (KOOS), the International Knee Documentation Committee (IKDC), T2 time on magnetic resonance imaging, and the Magnetic Resonance Observation Ca...

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