Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
ACE Report #11984
Ace Report Cover Arthroplasty

No Reduction in Pain or Opioid Consumption with Intra-Operative Ketamine vs Placebo in TKA

Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

Intraoperative Ketamine in Total Knee Arthroplasty Does Not Decrease Pain and Narcotic Consumption: A Prospective Randomized Controlled Trial

J Arthroplasty. 2019 Aug;34(8):1640-1645.

Contributing Authors: TL Tan AS Longenecker JH Rhee RP Good WD Emper KB Freedman JL Shaner JJ McComb EA Levicoff

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here


99 patients undergoing a primary unilateral total knee arthroplasty (TKA) were randomized to receive a 30mL infusion of ketamine or isotonic saline. The primary outcome of interest was pain as measured on a Visual Analog Scale (VAS). Secondary outcomes included narcotic consumption and the incidence of persistent opioid consumption. Results of the study revealed no significant differences in the a...

To view the full report, start your 30-day free trial today

No credit card required

JOIN Forgot Password?

Not sure if you want to join OrthoEvidence?

Access this report without an Account.

Success, an email containing a link to access this report has been sent to your inbox.

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.


Please Login or Join to leave comments.