Denervation therapy provides pain relief and functional improvement in knee OA up to 6 months

Study Type:Meta-analysis/Systematic Review

OE Level Evidence:1

Journal Level of Evidence:N/A

Effectiveness of Denervation Therapy on Pain and Joint Function for Patients with Refractory Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Pain Physician. 2019 Jul;22(4):341-352.

Contributing Authors: R Wang C Ma Y Han M Tan L Lu

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Synopsis

6 studies (408 patients) were included in this meta-analysis which investigated the efficacy of denervation therapy compared to control (sham; genicular nerve block; conventional analgesic therapy; intra-articular knee injections) for the relief of pain and improvement of function, up to 24 weeks post-treatment in patients with knee osteoarthritis. The outcomes of interest included pain on a Visua...